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Authors: N. Turk, A. Raza, P.C. Wuytens, H. Demol, A. Skirtach, K. Gevaert, R. Baets
Title: Towards SERS-based on-chip detection of protease activity using nanoplasmonic slot waveguides
Format: International Conference Presentation
Publication date: 11/2018
Journal/Conference/Book: 23th Annual Symposium of the IEEE Photonics Benelux Chapter

Abstract

Surface Enhanced Raman Spectroscopy (SERS) has already been successfully applied to detect protease activity in a microscope-based experiment. Here, we aimed to translate SERS-based protease activity monitoring to a cheaper, smaller and easier to use waveguide-based on-chip platform. Using nanoplasmonic slot waveguides we have for the first time detected SERS signal of a peptide substrate on a waveguide-based platform and are currently working on demonstrating SERS-based on-chip detection of protease activity.


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