|Authors: ||N. Turk, A. Raza, P.C. Wuytens, H. Demol, A. Skirtach, K. Gevaert, R. Baets|
|Title: ||Towards SERS-based on-chip detection of protease activity using nanoplasmonic slot waveguides|
|Format: ||International Conference Presentation|
|Publication date: ||11/2018|
|Journal/Conference/Book: ||23th Annual Symposium of the IEEE Photonics Benelux Chapter
Surface Enhanced Raman Spectroscopy (SERS) has already been successfully applied to detect protease activity in a microscope-based experiment. Here, we aimed to translate SERS-based protease activity monitoring to a cheaper, smaller and easier to use waveguide-based on-chip platform. Using nanoplasmonic slot waveguides we have for the first time detected SERS signal of a peptide substrate on a waveguide-based platform and are currently working on demonstrating SERS-based on-chip detection of protease activity.
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