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Authors: K. De Vos, J. Girones, T. Claes, E. Schacht, R. Baets, P. Bienstman
Title: High throughput label-free biosensing with silicon-on-insulator microring resonators
Format: International Conference Proceedings
Publication date: 3/2010
Journal/Conference/Book: Europt(r)ode X
Location: Czech Republic
Citations: Look up on Google Scholar
Download: Download this Publication (108KB) (108KB)


We have demonstrated simultaneous detection of multiple antibodies in a highly specific way. We discuss important considerations for high throughput sensing with silicon-on-insulator photonics, including detection limit, non-aggressive microfluidics packaging, receptor binding through a thin PEG layer, and camera based parallel readout. We introduce simultaneous measurement of refractive index and thickness of thin molecular layers, used to study conformational biomolecular changes.

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